Hypertonic saline in critical care: a review of the literature and guidelines for use in hypotensive states and raised intracranial pressure.

@article{Strandvik2009HypertonicSI,
  title={Hypertonic saline in critical care: a review of the literature and guidelines for use in hypotensive states and raised intracranial pressure.},
  author={G F Strandvik},
  journal={Anaesthesia},
  year={2009},
  volume={64 9},
  pages={990-1003}
}
Hypertonic saline has been in clinical use for many decades. Its osmotic and volume-expanding properties make it theoretically useful for a number of indications in critical care. This literature review evaluates the use of hypertonic saline in critical care. The putative mechanism of action is presented, followed by a narrative review of its clinical usefulness in critical care. The review was conducted using the Scottish Intercollegiate Guidelines Network method for the review of cohort… CONTINUE READING
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