Hypertonic Mannitol-Induced Hyperkalemia during Craniotomy

  title={Hypertonic Mannitol-Induced Hyperkalemia during Craniotomy},
  author={Masato Nakasuji and Masataka Nomura and Miwako Yoshioka and Taeko Miyata and Norie Imanaka and Masuji Tanaka},
We experienced two cases of mannitol-induced hyperkalemia during craniotomy for ruptured aneurysms. Hyperkalemia was first diagnosed by peaked T wave on the ECG. Serum potassium concentration in each patient was approximately 2 mEq/l higher than the baseline value, reaching 6.0 and 5.7 mEq/l, respectively, at 2 hours after completion of infusion of 45 and 30 g mannitol, respectively. Although the underlying mechanism was not elucidated, we recommend that patients with potassium concentration… CONTINUE READING
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