Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver.

@article{Alexander2003HyperthermicIH,
  title={Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver.},
  author={H. Richard Alexander and Steven K. Libutti and James F. Pingpank and Seth Steinberg and David L. Bartlett and Cynthia Helsabeck and Tatiana H. Beresneva},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2003},
  volume={9 17},
  pages={6343-9}
}
PURPOSE Liver metastases are the sole or life-limiting component of disease in the majority of patients with ocular melanoma who recur. Because median survival after diagnosis of liver metastases is short and no satisfactory treatment options exist, we have conducted clinical trials evaluating isolated hepatic perfusion (IHP) for patients afflicted with this condition. EXPERIMENTAL DESIGN Twenty-nine patients (male: 14, female: 15; mean age, 49 years) with unresectable liver metastases from… CONTINUE READING

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The biology of uveal melanoma

Cancer and Metastasis Reviews • 2017
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