Hyperthermia-driven aberrations of secreted microRNAs in breast cancer in vitro.

PURPOSE Expression profile alterations of nine breast cancer (BC)-associated secreted microRNAs (miRs) were determined under microenvironmental alterations occurring in tumour progression, metastasis or specific oncological treatment modalities. Thereto, the potential influence of the exogenic stimuli hypoxia, acidosis and hyperthermia was investigated in… CONTINUE READING