Hyperthermia: malformations to chaperones.

@article{Bennett2010HyperthermiaMT,
  title={Hyperthermia: malformations to chaperones.},
  author={Gregory D. Bennett},
  journal={Birth defects research. Part B, Developmental and reproductive toxicology},
  year={2010},
  volume={89 4},
  pages={
          279-88
        }
}
Hyperthermia has been known to induce malformations in numerous animal models as well being associated with human abnormalities. This was apparent particularly when the hyperthermia exposure was during the early stages of neural development. Although it was recognized relatively early that these exposures induced cell death, the specific molecular mechanism of how a brief heat exposure was translated in to specific cellular functions remains largely unknown. While our understanding of the… CONTINUE READING
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