Hypertensive disease of pregnancy and maternal mortality

@article{Lo2013HypertensiveDO,
  title={Hypertensive disease of pregnancy and maternal mortality},
  author={Jamie O. Lo and John F. Mission and Aaron B. Caughey},
  journal={Current Opinion in Obstetrics and Gynecology},
  year={2013},
  volume={25},
  pages={124–132}
}
Purpose of review The incidence of hypertensive disorders in pregnancy is increasing and is associated with maternal mortality worldwide. This review provides the obstetrician with an update of the current issues concerning hypertension and maternal mortality. Recent findings Preeclampsia affects about 3% of pregnancies, and all other hypertensive disorders complicate approximately 5–10% of pregnancies in the United States. In industrialized countries, rates of preeclampsia, gestational… Expand

Paper Mentions

Interventional Clinical Trial
A randomized non-inferiority trial of women with preeclampsia with severe features to determine if the addition of nonsteroidal anti-inflammatory drugs is inferior or non-inferior… Expand
ConditionsPreeclampsia Postpartum, Preeclampsia Severe
InterventionDrug
Hypertension in Pregnancy: Natural History and Treatment Options
TLDR
The evidence base for the pathophysiology and progression of hypertensive disorders in pregnancy, particularly pre-eclampsia, is reviewed and clinical algorithms and pharmacological agents for the management of hypertension in pregnancy are summarised, with a brief focus on post-partum considerations and long-term health implications. Expand
Hypertensive Disorders of Pregnancy: Overview and Current Recommendations
  • Diane M Folk
  • Medicine
  • Journal of midwifery & women's health
  • 2018
TLDR
The definitions of hypertensive disorders of pregnancy, diagnosis, pathophysiology of preeclampsia, indications for treatment, neurologic sequelae, and counseling about the implications of hypertension in pregnancy for subsequent health are reviewed. Expand
Hypertension in Pregnancy
Hypertensive disorders are most important clinical problem in pregnancy. Hypertension is one of the most frequently observed medical diseases, which considerably affects maternal and fetal morbidityExpand
Morbidity and maternal and infant outcomes of hypertensive disorder in pregnancy in China in 2018
TLDR
Morbidity varied across regions in China, with the lowest in Southwest and the highest in North China, and the low maternal mortality is related to the large‐scale development of standardized maternal health care in China. Expand
Preeclampsia and Hypertension in Pregnancy
TLDR
In this module, the physiologic blood pressure changes in pregnancy, the various hypertensive disorders of pregnancy, and the pathophysiology underlying preeclampsia are reviewed. Expand
Pharmacotherapy for hypertension in pregnant patients: special considerations
TLDR
Although there is a consensus that severe hypertension should be treated, treatment of mild hypertension without end-organ damage remains controversial and there is no agreement on when to initiate therapy, blood pressure targets or recommended drugs in the absence of robust evidence for the superiority of one drug over others. Expand
Hypertensive disease in pregnancy in Botswana: Prevalence and impact on perinatal outcomes.
TLDR
Improved management of hypertension in pregnancy may improve perinatal morbidity and mortality in Botswana and lead to a large number of adverse outcomes. Expand
Examining Biological and Psychological Variables in Hypertensive Disorders of Pregnancy
TLDR
A critical need exists to examine the relationship of perceived maternal distress and biomarker measures in the development of a hypertensive disorder during pregnancy in order to better understand this phenomenon. Expand
Maternal Mortality Predictors in Women with Hypertensive Disorders of Pregnancy: A Retrospective Cohort Study
TLDR
The case fatality rate of HDP was among the highest in the world and a delay in initiation of treatment because of delay in health care-seeking contributed to the majority of maternal deaths. Expand
Heart Disease in Pregnancy
TLDR
Proper risk assessment, prepregnancy counseling, and management of pregnancy in women with preexisting and acquired cardiovascular disease are best performed with a multidisciplinary team. Expand
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References

SHOWING 1-10 OF 76 REFERENCES
Maternal Hypertension and Associated Pregnancy Complications Among African‐American and Other Women in the united States
TLDR
The excess incidence of maternal hypertension, particularly chronic hypertension, may contribute to adverse maternal and fetal pregnancy outcome and the disparity in outcomes observed between African-American and other women in the U.S. Expand
Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.
TLDR
Determinants of pre-eclampsia rates include a bewildering array of risk and protective factors, including familial factors, sperm exposure, maternal smoking, pre-existing medical conditions (such as hypertension, diabetes mellitus and anti-phospholipid syndrome), and miscellaneous ones such as plurality, older maternal age and obesity. Expand
Hypertensive Pregnancy Disorders: Current Concepts
TLDR
Improved screening, and preventive and treatment strategies may not only optimize management of hypertensive pregnancy disorders, but may have a long‐term impact on women's cardiovascular events and outcomes years after the affected pregnancies. Expand
Severe Maternal Morbidity Associated with Hypertensive Disorders in Pregnancy in the United States
TLDR
Preeclampptic and eclamptic women younger than 20 years or older than 35 years had substantially higher morbidity, and African American women not only had higher incidence of hypertensive disorders in pregnancy but also tended to have a greater risk for most severe complications. Expand
Hypertensive disorders of pregnancy
  • Z. Zareian
  • Medicine
  • International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • 2004
TLDR
Hypertensive disorders of pregnancy commonly complicate pregnancy and have great influences on maternal and neonatal morbidity and mortality rates and more attention and precision is needed to evaluate the pregnant women for detecting and preventing the complications. Expand
Hypertensive Disorders and Severe Obstetric Morbidity in the United States
TLDR
The number of delivery hospitalizations in the United States with hypertensive disorders in pregnancy is increasing, and these hospitalizations are associated with a substantial burden of severe obstetric morbidity. Expand
Recurrence of hypertensive disorder in second pregnancy.
TLDR
Overweight and weight gain between pregnancies are associated with recurrent hypertensive disorders in pregnancy in women with gestational hypertension, a risk factor, independent of body weight. Expand
Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses.
TLDR
Women with a history of preeclampsia/eClampsia have approximately double the risk of early cardiac, cerebrovascular, and peripheral arterial disease, and cardiovascular mortality and further research is needed to determine the mechanisms underlying these associations and to identify effective prevention strategies. Expand
Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004.
TLDR
The observation of a small but consistent increase in preeclampsia is a conservative indication of a true population-level change in the United States, and may be exaggerated because of the revised clinical guidelines published in the 1990s. Expand
Maternal and perinatal outcome in pregnancies complicated with hypertensive disorder of pregnancy: a seven year experience of a tertiary care center
TLDR
Hypertensive disorder of pregnancy is associated with increased risk of maternal-perinatal adverse outcome and could be prevented by more widespread use of prenatal care, education of primary medical care personnel, prompt diagnosis of high-risk patients and timely referral to tertiary medical centers. Expand
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