Hypertension in infancy: diagnosis, management and outcome

  title={Hypertension in infancy: diagnosis, management and outcome},
  author={Janis M. Dionne and Carolyn L. Abitbol and Joseph T. Flynn},
  journal={Pediatric Nephrology},
Advances in the ability to identify, evaluate, and care for infants with hypertension, coupled with advances in the practice of Neonatology, have led to an increased awareness of hypertension in modern neonatal intensive care units. This review will present updated data on blood pressure values in neonates, with a focus on the changes that occur over the first days and weeks of life in both term and preterm infants. Optimal blood pressure measurement techniques as well as the differential… 

The hypertensive neonate.

  • J. Flynn
  • Medicine
    Seminars in fetal & neonatal medicine
  • 2020

Neonatal hypertension: cases, causes, and clinical approach

A case-based approach is taken to illustrate concepts and to point out important evidence gaps that need to be addressed so that management of neonatal hypertension may be improved.

Fifteen-minute consultation: Neonatal hypertension

There remains a relative paucity of data to guide the use of pharmacological therapies for hypertension in neonates, and Clinicians rely on empirical management protocols based on experience and expert opinion.

Neonatal hypertension.

  • J. Flynn
  • Medicine
    Le Journal medical libanais. The Lebanese medical journal
  • 2010
A careful diagnostic evaluation should lead to determination of the underlying cause of hypertension in most infants, although a small number may have persistent BP elevation throughout childhood.

Managing Hypertension in the Newborn Infants

Recent work on optimal BP measurement, definition, evaluation and management of hypertension as well as advances in drug therapy of neonatal hypertension are summarized.

Hypertension in Neonates: Need for Future Research

Hypertension in neonatal is labelled when as blood pressure (BP) is above 2 standard deviation or >95th percentile over the mean of systolic and/or diastolic BP in similar neonate with respect to

Hypertension in the neonatal period

  • J. Flynn
  • Medicine
    Current opinion in pediatrics
  • 2012
Understanding of neonatal hypertension continues to evolve, and better data are available on normal BP and the incidence of hypertension, but studies focused on appropriate treatment and long-term prognosis are still needed.

Pediatric hypertension: Review of the definition, diagnosis, and initial management

Neonatal hypertension: an educational review

The prognosis of neonatal hypertension remains largely unknown and thankfully most often resolves unless secondary to renovascular disease, but further research is needed.



Neonatal hypertension: diagnosis and management

  • J. Flynn
  • Medicine
    Pediatric Nephrology
  • 2000
In most cases hypertension will resolve, but some infants may require prolonged treatment, and therapy of neonatal hypertension should be tailored to the severity of the blood pressure elevation, and to the underlying cause of hypertension as appropriate.

Severe hypertension in children and adolescents: pathophysiology and treatment

A summary of the underlying causes and pathophysiology of acute severe hypertension in childhood as well as a detailed discussion of drug treatment and the optimal clinical approach to managing children and adolescents with acutesevere hypertension are provided.

Evaluation of the hypertensive infant: a rational approach to diagnosis.

Medically Resistant Neonatal Hypertension: Revisiting the Surgical Causes

The importance of searching for the surgical causes of pharmacologically resistant hypertension in the neonatal population and the consideration of surgical etiologies for differential diagnosis in neonates with severe hypertension that is unresponsive to pharmacological therapy is highlighted.

Dexamethasone and hypertension in preterm infants

The magnitude and duration of the effect of dexamethasone on systolic blood pressure has been examined in 13 very preterm infants and one infant developed hypertensive encephalopathy, demonstrating the need to monitor infants with CLD throughout steroid therapy and preferably for some days after it has ceased.

Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up

Antenatal steroid administration, maternal hypertension, umbilical arterial catheter, postnatal acute renal failure, patent ductus arteriosus, indomethacin treatment and chronic lung disease were associated with the development of neonatal hypertension.

An Unusual Case of Severe Therapy-Resistant Hypertension in a Newborn

A 2-day-old neonate with feeding intolerance and elevated blood pressure readings is described, and a nephrectomy secondary to medically uncontrollable hypertension and worsening cardiac dysfunction was performed.

Blood pressure in the first year of life in healthy infants born at term

Neonatal hypertension occurs in up to 2% of neonatal intensive care survivors and in up to 3% of all neonates. Normal blood pressure (BP) measurements are required to diagnose and manage

Hypertension and multicystic kidney.

A standard protocol for blood pressure measurement in the newborn.

A standard BP measurement protocol was studied to determine the effect of ensuring a restful state, startle response to cuff inflation, and infant position on BP in clinically stable low birth weight infants after the first week of life.