Hypertension and renal injury in experimental polycystic kidney disease.

@article{Kennefick1999HypertensionAR,
  title={Hypertension and renal injury in experimental polycystic kidney disease.},
  author={T M Kennefick and Muna A Al-Nimri and Terry T Oyama and Matthew M. Thompson and F. J. Kelly and Justin G Chapman and Sharon Anderson},
  journal={Kidney international},
  year={1999},
  volume={56 6},
  pages={2181-90}
}
UNLABELLED Hypertension and renal injury in experimental polycystic kidney disease. BACKGROUND Hypertension accelerates renal failure in autosomal dominant polycystic kidney disease (ADPKD), and evidence suggests a role for the renin-angiotensin system (RAS) in the functional and structural changes. To explore the hypothesis that RAS adaptations contribute to disease progression, we examined RAS activity and the long-term consequences of antihypertensive drugs, which suppress (enalapril) or… CONTINUE READING
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