Hypertension and renal failure (scleroderma renal crisis) in progressive systemic sclerosis. Review of a 25-year experience with 68 cases.

@article{Traub1983HypertensionAR,
  title={Hypertension and renal failure (scleroderma renal crisis) in progressive systemic sclerosis. Review of a 25-year experience with 68 cases.},
  author={Yehuda M. Traub and Alvin P. Shapiro and Gerald P. Rodnan and Thomas A Jr Medsger and Robert H. McDonald and Virginia D. Steen and T A Osial and Sanford F Tolchin},
  journal={Medicine},
  year={1983},
  volume={62 6},
  pages={335-52}
}
This paper reports the experiences of our group with 68 patients with progressive systemic sclerosis (PSS) admitted to hospitals of the University of Pittsburgh Health Center between 1955 and 1981 with scleroderma renal crisis (SRC). The onset of SRC was characterized by four features, namely, onset or aggravation, usually abrupt, of arterial hypertension; appearance of Grade III or IV retinopathy; elevations of peripheral renin activity to at least twice the upper limit of normal; and rapid… CONTINUE READING