Hypertension and insulin resistance.

  title={Hypertension and insulin resistance.},
  author={Brian N. C. Prichard and Christopher C. T. Smith and Saunak Sen and David John Betteridge},
  journal={Journal of cardiovascular pharmacology},
  volume={20 Suppl 11},
Insulin resistance and hyperinsulinemia is now recognized in non-insulin-dependent diabetes, essential hypertension, obesity, atherosclerotic heart disease, dyslipidemia, heart failure, and in heavy smokers. Several mechanisms have been proposed to explain hyperinsulinemia, insulin resistance and its relationship to hypertension; reduced sodium excretion, activation of the sympathetic nervous system, increased activity of the sodium/hydrogen pump, and stimulation of cellular growth. Some of the… CONTINUE READING
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