Hyperspectral fluorescence lifetime imaging for optical biopsy

@article{Nie2013HyperspectralFL,
  title={Hyperspectral fluorescence lifetime imaging for optical biopsy},
  author={Zhaojun Nie and Ran An and Joseph Hayward and Thomas J. Farrell and Qiyin Fang},
  journal={Journal of Biomedical Optics},
  year={2013},
  volume={18}
}
  • Zhaojun Nie, Ran An, +2 authors Q. Fang
  • Published 1 September 2013
  • Materials Science, Medicine, Engineering
  • Journal of Biomedical Optics
Abstract. A hyperspectral fluorescence lifetime imaging (FLIM) instrument is developed to study endogenous fluorophores in biological tissue as an optical biopsy tool. This instrument is able to spectrally, temporally, and spatially resolve fluorescence signal, thus providing multidimensional information to assist clinical tissue diagnosis. An acousto-optic tunable filter (AOTF) is used to realize rapid wavelength switch, and a photomultiplier tube and a high-speed digitizer are used to collect… Expand
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