Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging.

@article{Chaudhari2005HyperspectralAM,
  title={Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging.},
  author={Abhijit J. Chaudhari and Felix Darvas and James R. Bading and Rex A. Moats and Peter S. Conti and Desmond J. Smith and Simon R. Cherry and Richard M. Leahy},
  journal={Physics in medicine and biology},
  year={2005},
  volume={50 23},
  pages={5421-41}
}
For bioluminescence imaging studies in small animals, it is important to be able to accurately localize the three-dimensional (3D) distribution of the underlying bioluminescent source. The spectrum of light produced by the source that escapes the subject varies with the depth of the emission source because of the wavelength-dependence of the optical properties of tissue. Consequently, multispectral or hyperspectral data acquisition should help in the 3D localization of deep sources. In this… CONTINUE READING