Hypersensitivity to acoustic change in children with autism: electrophysiological evidence of left frontal cortex dysfunctioning.

@article{Gomot2002HypersensitivityTA,
  title={Hypersensitivity to acoustic change in children with autism: electrophysiological evidence of left frontal cortex dysfunctioning.},
  author={Marie Gomot and Marie-H{\'e}l{\`e}ne Giard and Jean-Louis Adrien and Catherine Barth{\'e}l{\'e}my and N. Nathalie Bruneau},
  journal={Psychophysiology},
  year={2002},
  volume={39 5},
  pages={
          577-84
        }
}
Exaggerated reactions to even small changes in the environment and abnormal behaviors in response to auditory stimuli are frequently observed in children with autism (CWA). Brain mechanisms involved in the automatic detection of auditory frequency change were studied using scalp potential and scalp current density (SCD) mapping of mismatch negativity (MMN) in 15 CWA matched with 15 healthy children. Compared with the response in controls, MMN recorded at the Fz site in CWA showed significantly… CONTINUE READING
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