Hypersensitivity of zidovudine: report of a case of anaphylaxis and review of the literature.

@article{Wassef1995HypersensitivityOZ,
  title={Hypersensitivity of zidovudine: report of a case of anaphylaxis and review of the literature.},
  author={Michel Wassef and Philip H. Keiser},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1995},
  volume={20 5},
  pages={1387-9}
}
Hypersensitivity to zidovudine is an uncommon complication of antiretroviral therapy. Manifestations range from isolated fever to anaphylaxis. Fever and rash are the most common features. Diagnosis is made by rechallenge, although some patients have antibodies to zidovudine. Treatment is supportive, and symptoms resolve on withdrawal of the medication.