Hypersensitivity in aseptic loosening of total hip replacements. The role of constituents of bone cement.

@article{Haddad1996HypersensitivityIA,
  title={Hypersensitivity in aseptic loosening of total hip replacements. The role of constituents of bone cement.},
  author={F. Haddad and A. Cobb and G. Bentley and N. Levell and P. Dowd},
  journal={The Journal of bone and joint surgery. British volume},
  year={1996},
  volume={78 4},
  pages={
          546-9
        }
}
Aseptic loosening is seen in a significant proportion of cemented total hip replacements (THR). In a small subgroup of patients who suffer early loosening polyethylene debris is unlikely to be responsible. We recently reported one case of allergic contact dermatitis to N,N-dimethylparatoluidine (DMT), an accelerator used in bone cement. We have therefore investigated this using skin-patch tests to a variety of substances including metals, polyethylene and the separated individual components of… Expand
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