Hyperprolactinemia from radiation-induced hypothalamic hypopituitarism.

  title={Hyperprolactinemia from radiation-induced hypothalamic hypopituitarism.},
  author={Gc Corkill and Frederick W. Hanson and Ernest M. Gold and Valerie A. White},
  journal={Surgical neurology},
  volume={13 1},
In 1975 Samaan et al described the effects of radiation damage of the hypothalamus in 15 patients with head and neck cancer. Shalet et al in 1977 described endocrine morbidity in adults who as children had been irradiated for brain tumors. This report describes instances of hyperprolactinemia and associated hypothalamic, pituitary, and thyroid dysfunction following irradiation of a young adult female for brain neoplasia.