Hyperprolactinemia and bone

@article{diFilippo2020HyperprolactinemiaAB,
  title={Hyperprolactinemia and bone},
  author={Luigi di Filippo and Mauro Doga and Eugenia Resmini and Andrea Giustina},
  journal={Pituitary},
  year={2020},
  volume={23},
  pages={314-321}
}
Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone. Patients with hyperprolactinemia did have often decreased bone mineral density as well as an increased risk of fractures. Since PRL control may be relevant to bone health… 
8 Citations
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