Hyperpolarized 3He magnetic resonance imaging ventilation defects in asthma: relationship to airway mechanics

@inproceedings{Leary2016Hyperpolarized3M,
  title={Hyperpolarized 3He magnetic resonance imaging ventilation defects in asthma: relationship to airway mechanics},
  author={Del Leary and Sarah Svenningsen and Fumin Guo and Swati Anil Bhatawadekar and Grace Parraga and Geoffrey N. Maksym},
  booktitle={Physiological reports},
  year={2016}
}
In patients with asthma, magnetic resonance imaging (MRI) provides direct measurements of regional ventilation heterogeneity, the etiology of which is not well-understood, nor is the relationship of ventilation abnormalities with lung mechanics. In addition, respiratory resistance and reactance are often abnormal in asthmatics and the frequency dependence of respiratory resistance is thought to reflect ventilation heterogeneity. We acquiredMRIventilation defect maps, forced expiratory volume in… CONTINUE READING
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