Hyperplastic proliferations of the ECL cells.

@article{Dayal1992HyperplasticPO,
  title={Hyperplastic proliferations of the ECL cells.},
  author={Yogeshwar Dayal},
  journal={The Yale Journal of Biology and Medicine},
  year={1992},
  volume={65},
  pages={805 - 829}
}
Enterochromaffin-like (ECL) cells are the dominant endocrine cell type in the oxyntic mucosa. Normally regarded as histamine-producing cells, they are exquisitely sensitive to the trophic action of gastrin and undergo a hyperplastic increase in a variety of hypergastrinemic conditions. A hyperplasia-neoplasia sequence of ECL-cell proliferations has been recently proposed, following the realization that increasingly severe degrees of ECL-cell hyperplasias over a period of several years can… CONTINUE READING

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