Hyperphosphorylated tau in the brains of mice and monkeys with long-term administration of ketamine.

@article{Yeung2010HyperphosphorylatedTI,
  title={Hyperphosphorylated tau in the brains of mice and monkeys with long-term administration of ketamine.},
  author={Lok Y Yeung and Maria Sen Mun Wai and Ming Fan and Ying Tat Mak and Wai Ping Lam and Zhen Li and Gang Lu and David Tai Wai Yew},
  journal={Toxicology letters},
  year={2010},
  volume={193 2},
  pages={189-93}
}
Ketamine, a non-competitive antagonist at the glutamatergic N-methyl-d-aspartate (NMDA) receptor, might impair memory function of the brain. Loss of memory is also a characteristic of aging and Alzheimer's disease. Hyperphosphorylation of tau is an early event in the aging process and Alzheimer's disease. Therefore, we aimed to find out whether long-term ketmaine administration is related to hyperphosphorylation of tau or not in the brains of mice and monkeys. Results showed that after 6 months… CONTINUE READING
Highly Cited
This paper has 27 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Similar Papers

Loading similar papers…