Hyperosmolarity leads to an increase in derepressed system A activity in the renal epithelial cell line NBL-1.

Abstract

Hyperosmolarity induced an increase in Na(+)-dependent L-alanine uptake in confluent monolayers of the established renal epithelial cell line NBL-1. This induction was attributable to system A and was only seen when the cells had been previously deprived of amino acids in the culture medium to derepress system A activity. It was additive to the adaptive… (More)

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@article{Soler1993HyperosmolarityLT, title={Hyperosmolarity leads to an increase in derepressed system A activity in the renal epithelial cell line NBL-1.}, author={C. Soler and Antonio Felipe and F. Javier Casado and John D. McGivan and Marçal Pastor-Anglada}, journal={The Biochemical journal}, year={1993}, volume={289 ( Pt 3)}, pages={653-8} }