Hypermutation and stress adaptation in bacteria

@article{Jayaraman2011HypermutationAS,
  title={Hypermutation and stress adaptation in bacteria},
  author={Rajshri Jayaraman},
  journal={Journal of Genetics},
  year={2011},
  volume={90},
  pages={383-391}
}
Hypermutability is a phenotype characterized by a moderate to high elevation of spontaneous mutation rates and could result from DNA replication errors, defects in error correction mechanisms and many other causes. The elevated mutation rates are helpful to organisms to adapt to sudden and unforeseen threats to survival. At the same time hypermutability also leads to the generation of many deleterious mutations which offset its adaptive value and therefore disadvantageous. Nevertheless, it is… CONTINUE READING
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