Hypermethylation of the GATA genes in lung cancer.

  title={Hypermethylation of the GATA genes in lung cancer.},
  author={Mingzhou Guo and Yoshimitsu Akiyama and Michael G. House and Craig M. Hooker and Elizabeth I. Heath and Edward W. Gabrielson and Stephen Chi-Tin Yang and Yu Ling Han and Stephen B. Baylin and James G. Herman and Malcolm V. Brock},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={10 23},
PURPOSE In lung cancer, DNA hypermethylation is known to be a common event. EXPERIMENTAL DESIGN Gene expression and methylation status of GATA-4, GATA-5, and GATA-6 were analyzed with cell lines and primary human lung cancers. Methylation profiles of primary lung cancers were analyzed and correlated with clinical as well as histopathological data… CONTINUE READING