Hypermetabolism, organ failure, and metabolic support.

  title={Hypermetabolism, organ failure, and metabolic support.},
  author={Frank B. Cerra},
  volume={101 1},
The hypermetabolism organ failure complex remains the predominant reason for both prolonged stay and death in the surgical intensive care unit. What was perceived as isolated organ failure, such as adult respiratory distress syndrome, is now seen as part of the systemic response to injury and repair. Sepsis has become the systemic inflammatory response due to invading microorganisms. What was once perceived as diagnostic of sepsis has been recognized after severe perfusion deficits and in the… CONTINUE READING


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