Hyperlipidemic Pancreatitis in a Primigravida Adolescent


Acute pancreatitis complicating pregnancy occurs very rare ly. Its incidence has been estimated at between one in 1000 and one in 3000 (1± 3). Chole lithiasis is the most commonly associate d cause (17 to 90% of the cases) followed by hyperlipidemia. Other cause s are : acute hepatic steatosis, preeclampsia, hypercalcemia, hype rparathyroidism, infections and drugs like hydrochlorothiazid e, furosemide , sulfurs, metronidazole , corticoste roids, tetracycline s, estrogens, and methyldopa (2, 4 ± 6). Gestational pancreatitis carries a signi® cant risk of mortality for both mother and fetus: up to 37% and up to 13.5% respective ly (3, 6, 7). The important elements in diagnosis are : 1) clinical symptoms; 2) high serum amylase and lipase which are not indispensable for the diagnosis, principally in hyperlipidemic patients, who can have normal amylasemia; 3) compatible ultrasonography; 4) computerized tomography (only at the end of pregnancy) (2± 4, 5). Early diagnosis, adequate observation, and control of the mother’ s and fetus’ s vitality reduce complications such as pseudocysts, abcesses, and maternal and fetal mortality rates (3). The patients should be carefully informed about postpartum contraceptive s, particularly the avoidance of synthe tic estrogens in cases of hyperlipidemia (3). It is very important to search for the cause of the pancreatitis in order to treat and prevent new acute episodes. We report a case of hypertriglyceridemia-induce d pancreatitis occurring during pregnancy in a primigravida adole scent.

DOI: 10.1023/A:1018854012263

Cite this paper

@article{Knobell1998HyperlipidemicPI, title={Hyperlipidemic Pancreatitis in a Primigravida Adolescent}, author={Roxana Knobell and L{\'u}cia Nassi Castilho and Renato Passini and Lucia S. Parentoni and Eliana Cotta de Faria}, journal={Digestive Diseases and Sciences}, year={1998}, volume={43}, pages={943-944} }