Hyperlipidemia and the progression of renal disease.

  title={Hyperlipidemia and the progression of renal disease.},
  author={William F. Keane and Bertram L. Kasiske and Mary Pat O'Donnell},
  journal={The American journal of clinical nutrition},
  volume={47 1},
Focal glomerulosclerosis (FGS) is commonly seen in human and in experimental models of chronic renal disease. Although considerable experimental data suggest that hypertension is important in progressive nephron damage, recent studies also have indicated that abnormal lipid metabolism may be an independent risk factor in the pathogenesis of FGS. Indeed, the synergistic impact of hypertension and hyperlipidemia in the pathogenesis of FGS may be analogous to the role of these factors in the… CONTINUE READING

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