Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis.

  title={Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis.},
  author={Margherita Longo and Andrea Crosignani and Pier Maria Battezzati and C Squarcia Giussani and Paolo Invernizzi and Marco Zuin and Mauro Podda},
  volume={51 2},
BACKGROUND Primary biliary cirrhosis (PBC), a chronic cholestatic liver disease, is frequently associated with severe hypercholesterolaemia but the clinical significance of this finding is unclear. AIMS To characterise changes in serum lipid profile over time and to assess the risk of cardiovascular disease in PBC. SUBJECTS AND METHODS We studied a cohort of 400 PBC patients for 6.2 years (range 4 months to 24 years) by serial determinations of serum lipid levels and registration of all… CONTINUE READING