Hyperkalemia and trimethoprim-sulfamethoxazole.
@article{Ellison1997HyperkalemiaAT, title={Hyperkalemia and trimethoprim-sulfamethoxazole.}, author={David H. Ellison}, journal={American journal of kidney diseases : the official journal of the National Kidney Foundation}, year={1997}, volume={29 6}, pages={ 959-62; discussion 962-5 } }
3 Citations
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Two well-established models of cortical collecting tubule ion transport were investigated to investigate the effects of pentamidine on renal tubular Na+ reabsorption and, therefore, K+ secretion and the causes of hyperkalemia.
Hyponatraemia associated with trimethoprim and a diuretic.
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It is believed that a comprehensive review of the existing data should be carried out and that properly designed long term prospective studies on the effects of different levels of alcohol consumption on health should be undertaken.
Brief report: trimethoprim-induced hyperkalemia in a patient with AIDS.
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It is found that hyperkalemia develops in 20 to 53 percent of patients with AIDS while they are receiving high doses of trimethoprim in combination with sulfamethoxazole or dapsone for the treatment of Pneumocystis carinii pneumonia.
Hyporeninemic hypoaldosteronism associated with acquired immune deficiency syndrome.
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K(+)-sparing diuretic actions of trimethoprim: inhibition of Na+ channels in A6 distal nephron cells.
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Investigation of the effect of TMP on the 4 pS, highly selective Na+ channel in the apical membrane of A6 cells grown on permeable supports in the presence of 1.5 microM aldosterone found the appearance of a new closed state after apical TMP treatment was revealed.
Trimethoprim and tetracycline inhibit airway epithelial sodium absorption.
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This study has identified two antibacterial agents that also reduce the Na+ absorption found in CF and these drugs may offer combined effects for the treatment of CF.
Hyperkalemia in Elderly Patients Receiving Standard Doses of Trimethoprim-Sulfamethoxazole
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The temporal association of trimethoprim use with hyperkalemia in this patient strongly suggests a causal role and it would be interesting to see if this association is confirmed in a large clinical trial, especially in older persons with some degree of age-related renal insufficiency.
Hyperkalemia in Hospitalized Patients Treated with Trimethoprim-Sulfamethoxazole
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Evaluating the effect of standard-dose trimethoprim-sulfamethoxazole on the development of hyperkalemia in hospitalized patients treated for various infectious processes found no change in potassium homeostasis or renal function.
Renal Mechanism of Trimethoprim-induced Hyperkalemia
- Medicine, BiologyAnnals of Internal Medicine
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The purpose of this study was to test the hypothesis that trimethoprim causes hyperkalemia by a direct action on the distal nephron cells responsible for secreting potassium by conducting microperfusion of Distal Tubules.
Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone.
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In patients with AIDS, oral therapy with trimethoprim-sulfamethoxazole and with trimetrim-dapsone are equally effective for mild-to-moderate first episodes of P. carinii pneumonia, but with trimmedethopim- dapsone there are fewer serious adverse reactions than with trimETHoprim.