Hyperinsulinism in infants and children.

  title={Hyperinsulinism in infants and children.},
  author={Charles A. Stanley},
  journal={Pediatric clinics of North America},
  volume={44 2},
Hyperinsulinism is the most common cause of hypoglycemia in early infancy. Congenital hyperinsulinism, formerly termed nesidioblastosis, is usually caused by genetic defects in beta-cell regulation, including a severe recessive disorder of the sulfonylurea receptor, a milder dominant form of hyperinsulinism, and a syndrome of hyperinsulinism plus hyperammonemia. Transient neonatal hyperinsulinism may be associated with perinatal asphyxia or small-for-dates birthweight and maternal diabetes. To… CONTINUE READING
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