Hyperinsulinemic syndrome: the metabolic syndrome is broader than you think.

  title={Hyperinsulinemic syndrome: the metabolic syndrome is broader than you think.},
  author={Christopher T Kelly and Janet Mansoor and Gerald L Dohm and William H H Chapman and John R. Pender and Walter J. Pories},
  volume={156 2},
BACKGROUND Type 2 diabetes mellitus (T2DM) is characterized by hyperinsulinemia. In 2011 we showed that gastric bypass (RYGB) corrects these high levels even though insulin resistance remains high, ie, the operation "dissociates" hyperinsulinemia from insulin resistance. RYGB produces reversal of T2DM along with other diseases associated with the metabolic syndrome. This observation led us to examine whether these illnesses also were characterized by hyperinsulinemia. METHODS A systematic… CONTINUE READING
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