Hyperinsulinaemia and Na+, K(+)-ATPase activity in thyrotoxic periodic paralysis.

@article{Chan1994HyperinsulinaemiaAN,
  title={Hyperinsulinaemia and Na+, K(+)-ATPase activity in thyrotoxic periodic paralysis.},
  author={Amy Bik-Wan Chan and Rahul Shinde and C. Channing Chow and Clive Stewart Cockram and Ramasamyiyer Swaminathan},
  journal={Clinical endocrinology},
  year={1994},
  volume={41 2},
  pages={213-6}
}
OBJECTIVE Thyrotoxic periodic paralysis (TPP) usually follows a heavy carbohydrate meal and this may be explained by hyperinsulinaemia stimulating Na+, K(+)-ATPase activity. To clarify this the effect of glucose load on serum insulin concentration and platelet Na+, K(+)-ATPase activity in thyrotoxic periodic paralysis (TPP) was examined. DESIGN In all subjects a standard 75-g glucose tolerance test was done and blood samples were taken at 0, 1 and 2 hours. SUBJECTS Twenty-five healthy… CONTINUE READING

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