Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis

  title={Hyperhomocysteinemia is associated with cognitive impairment in multiple sclerosis},
  author={Cinzia Dello Russo and Francesco Morabito and Francesca Luise and Angela Piromalli and Luigi Battaglia and Alessio Vinci and Vincenzo Trapani Lombardo and Vanessa Luciene Abreu de Marco and Paolo Morabito and Francesca Condino and Aldo Quattrone and Umberto Aguglia},
  journal={Journal of Neurology},
Hyperhomocysteinemia (HHcy) has been associated with cognitive impairment in various neurological diseases. Cognitive impairment occurs early in multiple sclerosis (MS). Conflicting data have been reported regarding plasma total homocysteine (tHcy) levels in MS patients, and the impact of HHcy on cognitive impairment in MS is not known. This study investigated whether plasma total homocysteine levels are increased in MS and if HHcy is associated with cognitive impairment in MS. We compared tHcy… CONTINUE READING

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