Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study

@article{Romagnuolo2001HyperhomocysteinemiaAI,
  title={Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study},
  author={Joseph Romagnuolo and Richard N Fedorak and Valerian C Dias and Fiona Bamforth and Marty Teltscher},
  journal={American Journal of Gastroenterology},
  year={2001},
  volume={96},
  pages={2143-2149}
}
OBJECTIVE:Homocysteine is a sulfur-containing amino acid formed during the demethylation of methionine. Vitamin B12 and folate deficiency and therapy with antifolate drugs may predispose patients with inflammatory bowel disease (IBD) to hyperhomocysteinemia. The known associations between hyperhomocysteinemia and smoking, osteoporosis, and thrombosis make it an interesting candidate as a pathogenetic link in IBD. The aim of this study was to identify the prevalence and risk factors of… CONTINUE READING