Hyperhomocysteinemia, endothelial nitric oxide synthase polymorphism, and risk of coronary artery disease.

@article{Kerkeni2006HyperhomocysteinemiaEN,
  title={Hyperhomocysteinemia, endothelial nitric oxide synthase polymorphism, and risk of coronary artery disease.},
  author={Mohsen Kerkeni and Faouzi Addad and Maryline Chauffert and Anne Myara and Mohamed Ben Farhat and Abdelh{\'e}di Miled and Khira Maaroufi and François Trivin},
  journal={Clinical chemistry},
  year={2006},
  volume={52 1},
  pages={53-8}
}
BACKGROUND Hyperhomocysteinemia is an independent, graded risk factor for coronary artery disease (CAD). The G894T variant of endothelial nitric oxide synthase (eNOS) was postulated to be associated with hyperhomocysteinemia and could influence individual susceptibility to CAD. The aims of this study were to investigate (a) the relationship of the eNOS G894T polymorphism with the presence and the severity of CAD and (b) the possible relationship between hyperhomocysteinemia and the eNOS G894T… CONTINUE READING