Hyperglycemia during hypothermic cardiopulmonary bypass does not alter postbypass vascular endothelial responses in dogs.

@article{Odwyer1996HyperglycemiaDH,
  title={Hyperglycemia during hypothermic cardiopulmonary bypass does not alter postbypass vascular endothelial responses in dogs.},
  author={Cliona O'dwyer and A E Feerick and O S Steinsland and Yue Wang and Cheng Yie Lin and William E. Johnston},
  journal={Journal of cardiothoracic and vascular anesthesia},
  year={1996},
  volume={10 5},
  pages={614-8}
}
BACKGROUND Hyperglycemia during hypothermic cardiopulmonary bypass (CPB) may alter intrinsic vasomotion by reducing endothelial-dependent vasorelaxation. Using a canine model of hypothermic CPB, this study tested whether hyperglycemia altered the vasodilator response to acetylcholine (ACh) and the vasoconstrictor response to phenylephrine (Phe). METHODS… CONTINUE READING