Hyperglycemia and QT interval: time for re-evaluation.

  title={Hyperglycemia and QT interval: time for re-evaluation.},
  author={Raffaele Marfella and Franco Schmidt Rossi and Dario Giugliano},
  journal={Diabetes, nutrition & metabolism},
  volume={14 2},
Among the many mechanisms proposed to explain the relationship between glucose levels and subsequent cardiovascular events, a prolonged QT interval, ie the time interval between the start of activation of the ventricle and completion of its repolarization, seems noteworthy. In Type 2 diabetic patients, for example, the prevalence of QTc (corrected QT interval) prolongation is as high as 26% and is associated with heart disease. The mechanism by which hyperglycemia may produce ventricular… CONTINUE READING