Hyperglycaemic hypoxia alters after-potential and fast K+ conductance of rat axons by cytoplasmic acidification.

@article{Schneider1993HyperglycaemicHA,
  title={Hyperglycaemic hypoxia alters after-potential and fast K+ conductance of rat axons by cytoplasmic acidification.},
  author={Udo Schneider and Stefan Quasthoff and Nenad R. Mitrovi{\'c} and Peter Grafe},
  journal={The Journal of physiology},
  year={1993},
  volume={465},
  pages={679-97}
}
1. The effects of hyperglycaemic hypoxia (a condition possibly involved in the pathogenesis of diabetic neuropathy) on the depolarizing after-potential and the potassium conductance of myelinated rat spinal root axons were investigated using electrophysiological recordings from intact spinal roots and from excised, inside-out axonal membrane patches. 2. Isolated spinal roots were exposed to hypoxia in solutions containing normal or high glucose concentrations. The depolarizing after-potential… CONTINUE READING

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