Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose.

@article{Nakagawa2002HyperglycaemiaST,
  title={Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose.},
  author={Eiichiro Nakagawa and Noritoshi Nagaya and Hiroyuki Okumura and Mitsunobu Enomoto and Hideo Oya and Fumiaki Ono and Hiroshi Hosoda and Masayasu Kojima and Kenji Kangawa},
  journal={Clinical science},
  year={2002},
  volume={103 3},
  pages={
          325-8
        }
}
Ghrelin is a novel growth hormone (GH)-releasing peptide, isolated from the stomach, which may also cause a positive energy balance by stimulating food intake and reducing fat utilization. However, whether glucose influences the release of ghrelin remains unknown. Accordingly, we examined circulating levels of ghrelin and GH in response to the intravenous or oral administration of 50 g of glucose in eight healthy humans. After the administration of intravenous glucose (50 g), the plasma ghrelin… CONTINUE READING
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