Hyperghrelinemia precedes obesity in Prader-Willi syndrome.

@article{Feigerlov2008HyperghrelinemiaPO,
  title={Hyperghrelinemia precedes obesity in Prader-Willi syndrome.},
  author={Eva Feigerlov{\'a} and Gwena{\"e}lle Diene and Françoise Conte-Auriol and Catherine Molinas and Isabelle Gennero and J Y Salles and Catherine Arnaud and Ma{\"i}th{\'e} Tauber},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 7},
  pages={2800-5}
}
BACKGROUND High plasma ghrelin levels have been reported in Prader-Willi syndrome (PWS). However, little is known about plasma ghrelin in these children during the first years of life characterized by a failure to thrive. OBJECTIVE The objective of the study was to investigate total plasma ghrelin levels in children with PWS and controls from 2 months to 17 years. SUBJECTS AND METHODS Forty children with PWS [24 boys, 16 girls, median age 3.6 yr, median body mass index (BMI) Z-score 0.3… CONTINUE READING

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