Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.

@article{Brizel1998HyperfractionatedIW,
  title={Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.},
  author={David M. Brizel and Mieke Albers and Samuel Rowland Fisher and Richard Scher and William J. Richtsmeier and Vera H{\'a}rs and Stephen L. George and Andrew Tsao Huang and Leonard R. Prosnitz},
  journal={The New England journal of medicine},
  year={1998},
  volume={338 25},
  pages={
          1798-804
        }
}
BACKGROUND Radiotherapy is often the primary treatment for advanced head and neck cancer, but the rates of locoregional recurrence are high and survival is poor. We investigated whether hyperfractionated irradiation plus concurrent chemotherapy (combined treatment) is superior to hyperfractionated irradiation alone. METHODS Patients with advanced head and neck cancer who were treated only with hyperfractionated irradiation received 125 cGy twice daily, for a total of 7500 cGy. Patients in the… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 363 CITATIONS, ESTIMATED 34% COVERAGE

2 Hypopharyngeal Cancer

VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

M6P/IGF2R loss of heterozygosity in head and neck cancer associated with poor patient prognosis

VIEW 7 EXCERPTS
CITES METHODS, BACKGROUND & RESULTS
HIGHLY INFLUENCED

Enteral feeding tubes in patients undergoing definitive chemoradiation therapy for head-and-neck cancer: a critical review.

  • International journal of radiation oncology, biology, physics
  • 2012
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1999
2019

CITATION STATISTICS

  • 16 Highly Influenced Citations

  • Averaged 10 Citations per year over the last 3 years

Similar Papers

Loading similar papers…