Hyperfiltration and renal disease in glycogen storage disease, type I.

@article{Baker1989HyperfiltrationAR,
  title={Hyperfiltration and renal disease in glycogen storage disease, type I.},
  author={L A Baker and Stephen Dahlem and Stanley Goldfarb and Eric Kern and Charles A. Stanley and Joseph Egler and Jeffrey S Olshan and Samuel N Heyman},
  journal={Kidney international},
  year={1989},
  volume={35 6},
  pages={1345-50}
}
A prospective study of 14 patients (ages 6 months to 33 years) with glycogen storage disease, Type I (GSD-I) was carried out in order to define the character and frequency of renal dysfunction. A marked increase in the glomerular filtration rate (GFR) was documented in virtually all subjects, with the mean GFR raised by approximately 50%, to the range of 170 ml/min/1.73 m2. While this constituted the only renal abnormality found in the younger patients, a significant increase in urinary albumin… CONTINUE READING

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