Hyperfibrinogenemia is a useful predictor for lymphatic metastasis in human gastric cancer.

@article{Yamashita2005HyperfibrinogenemiaIA,
  title={Hyperfibrinogenemia is a useful predictor for lymphatic metastasis in human gastric cancer.},
  author={Hiroharu Yamashita and Joji Kitayama and Hirokazu Nagawa},
  journal={Japanese journal of clinical oncology},
  year={2005},
  volume={35 10},
  pages={595-600}
}
BACKGROUND Although abnormal hemostasis has been described in cancer patients, the precise association between the plasma fibrinogen level and lymphatic metastasis has not been reported in a large-scale clinical study. METHODS Preoperative plasma levels of fibrinogen as well as C-reactive protein (CRP) and carcinoembryonic antigen (CEA) were retrospectively examined in 649 patients who underwent surgery for gastric cancer, and the correlation between these factors and nodal status was… CONTINUE READING

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