Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes.


The underlying mechanisms of reactive macrophage activation syndromes (rMAS) are not understood in detail, and there is no specific treatment. This observational study was prompted by intravenous immunoglobulin (IVIG), dramatically halting two distinct rMAS episodes in the same patient. We evaluated the potential benefits of IVIG administration in treating… (More)


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