Hyperechogenicity of the substantia nigra in healthy controls is related to MRI changes and to neuronal loss as determined by F-Dopa PET

Abstract

Transcranial ultrasound (TCS) has been shown to reveal hyperechogenicity of the substantia nigra (SN) in Parkinsonian patients and in about 10% of healthy controls. It is hypothesized that SN hyperechogenicity in healthy subjects is a vulnerability marker for idiopathic Parkinson's disease (IPD). Although there is strong evidence that the echomarker results… (More)
DOI: 10.1016/j.neuroimage.2009.05.072

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@article{Behnke2009HyperechogenicityOT, title={Hyperechogenicity of the substantia nigra in healthy controls is related to MRI changes and to neuronal loss as determined by F-Dopa PET}, author={S. Behnke and U. Schroeder and U. Dillmann and Hans-Georg Buchholz and Mathias Schreckenberger and G. Fuss and W. Reith and D. Berg and C. M. Krick}, journal={NeuroImage}, year={2009}, volume={47 4}, pages={1237-43} }