Hypercortisolism is associated with increased coronary arterial atherosclerosis: analysis of noninvasive coronary angiography using multidetector computerized tomography.

@article{Neary2013HypercortisolismIA,
  title={Hypercortisolism is associated with increased coronary arterial atherosclerosis: analysis of noninvasive coronary angiography using multidetector computerized tomography.},
  author={Nicola Marguerite Neary and Oscar Julian Booker and Brent S. Abel and Jatin Raj Matta and Nancy A Muldoon and Ninet Sinaii and Roderic I. Pettigrew and Lynnette K Nieman and Ahmed M. Gharib},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2013},
  volume={98 5},
  pages={
          2045-52
        }
}
BACKGROUND Observational studies show that glucocorticoid therapy and the endogenous hypercortisolism of Cushing's syndrome (CS) are associated with increased rates of cardiovascular morbidity and mortality. However, the causes of these findings remain largely unknown. OBJECTIVE To determine whether CS patients have increased coronary atherosclerosis. DESIGN A prospective case-control study was performed. SETTING Subjects were evaulated in a clinical research center. SUBJECTS Fifteen… CONTINUE READING
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