Hypercortisolism in alcohol dependence and its relation to hippocampal volume loss.

  title={Hypercortisolism in alcohol dependence and its relation to hippocampal volume loss.},
  author={Thomas P. Beresford and David B. Arciniegas and Julie Alfers and L. J. Clapp and Brandon K Martin and Henry F. Beresford and Yiping Du and Dengfeng Liu and Dinggang Shen and Christos Davatzikos and Mark L Laudenslager},
  journal={Journal of studies on alcohol},
  volume={67 6},
OBJECTIVE The effects of hypercortisolism on hippocampal volume have not been studied in heavy drinkers. Prior work suggested increased hypothalamic-pituitary-adrenal activity in relation to lowered total hippocampus volume (THV) in heavy-drinking alcohol-dependent (AD) subjects. The present study hypothesized the following: (1) that chronic heavy-drinking subjects would demonstrate significantly higher salivary cortisol concentrations than light-drinking control subjects and (2) that data from… CONTINUE READING
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Statistical Power Analysis for the Behavioral Sciences, 2nd Edition

  • J. COHEN
  • Mahwah, NJ: Lawrence Erlbaum,
  • 1988
Highly Influential
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