Hypercortisolemic depression is associated with the metabolic syndrome in late-life.

  title={Hypercortisolemic depression is associated with the metabolic syndrome in late-life.},
  author={Nicole Vogelzangs and Kristen M Suthers and Luigi Ferrucci and Eleanor M. Simonsick and Alessandro Ble and Matthew A Schrager and Stefania Bandinelli and Fulvio Lauretani and Sandra V Giannelli and Brenda W J H Penninx},
  volume={32 2},
INTRODUCTION Depression has been hypothesized to be associated with metabolic abnormalities which increase the risk of cardiovascular disease (CVD) and diabetes. Such a link could be due to increased HPA-axis activity. This study investigates the cross-sectional relationship between depression, urinary cortisol and metabolic syndrome in an older population. METHODS Data are from 867 participants of the InChianti Study, aged 65 years. Depressive symptoms were assessed using the CES-D scale… CONTINUE READING