Hypercholesterolemia in Youth: Opportunities and Obstacles to Prevent Premature Atherosclerotic Cardiovascular Disease

@article{McNeal2010HypercholesterolemiaIY,
  title={Hypercholesterolemia in Youth: Opportunities and Obstacles to Prevent Premature Atherosclerotic Cardiovascular Disease},
  author={Catherine J. McNeal and Tala Dajani and Don P. Wilson and Andrea E. Cassidy-Bushrow and Justin B. Dickerson and Marcia G Ory},
  journal={Current Atherosclerosis Reports},
  year={2010},
  volume={12},
  pages={20-28}
}
Treatment of hypercholesterolemia in youth is predicated on the knowledge that we can identify those youth with this atherosclerotic risk factor most likely to develop premature cardiovascular disease. Unfortunately, this is not the case. Before we can adequately address appropriate lipid-lowering therapies in this special population, we must address and resolve current barriers related to screening and diagnosis. In this article, we describe some of the opportunities and obstacles that… 
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Current guidelines for lipid screening in the USA and the rationale for the guidelines are described, including evolution of the guidelines, controversies regarding universal lipid screening, and differences between the pediatric and adult lipid screening guidelines.
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A clear difference was found between boys and girls with T1D in the presence of individual CVD risk factors as well as in overall CVDrisk profiles; the girls were on the whole more impacted.
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The purpose of this paper is to review and summarize the most current evidence-based research findings and guidelines on screening, diagnosis, and management of children and adolescents (ages 2-18) with heFH.
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Research suggests that dietary fibers may prevent obesity and lower blood cholesterol levels with a favourable impact on the risk of future cardiovascular disease incidence, but it is for further studies to assess whether also in Southern European Countries, practicing Mediterranean diet as a normal habit, dietary fiber may contribute to modify the relatively low proportion of hyperlipemia observed in this population.
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Saturated fat was associated with elevated lipid levels in obese children and the results reinforce the importance of healthy dietary habits since child-hood in order to reduce the risks of cardiovascular diseases in adulthood.
Decreased prevalence of hypercholesterolaemia and stabilisation of obesity trends in 5-year-old children: possible effects of changed public health policies.
TLDR
The anthropometric characteristics and total cholesterol levels in a population of 5-year-old children and the prevalence of overweight/obesity and hypercholesterolaemia in these children over a period of 8 years have been investigated to describe a negative trend in the prevalence in pre-pubertal children.
Learning more about dyslipidemia in childhood.
Aldosterone contributes to elevated left ventricular mass in black boys
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The results suggest the following model in black males: increased aldosterone leads to increased sodium retention, causing a volume-mediated increase in blood pressure; increased blood pressure results in increased left ventricular mass, and eventually LVH.
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