Hypercholesterolemia exacerbates ventricular remodeling in the rat model of myocardial infarction.

@article{Mczewski2006HypercholesterolemiaEV,
  title={Hypercholesterolemia exacerbates ventricular remodeling in the rat model of myocardial infarction.},
  author={Michał Mączewski and Joanna Mączewska},
  journal={Journal of cardiac failure},
  year={2006},
  volume={12 5},
  pages={399-405}
}
BACKGROUND Detrimental left ventricular (LV) remodeling is exacerbated in hypercholesterolemic patients with myocardial infarction; however, this could result from either larger infarcts or more extensive remodeling itself in this population. Therefore, we sought to investigate whether high cholesterol feeding exacerbates LV remodeling and heart failure in rats with myocardial infarction independently from its influence on infarct size. METHODS AND RESULTS Myocardial infarction was induced by… CONTINUE READING

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