Hypercalcemia with nephrocalcinosis and impaired renal function due to increased Parathyroid hormone secretion at onset of childhood acute lymphoblastic leukemia.

@article{Lankisch2004HypercalcemiaWN,
  title={Hypercalcemia with nephrocalcinosis and impaired renal function due to increased Parathyroid hormone secretion at onset of childhood acute lymphoblastic leukemia.},
  author={Petra Lankisch and Christof Maria Kramm and Derik Hermsen and Ruediger Wessalowski},
  journal={Leukemia & lymphoma},
  year={2004},
  volume={45 8},
  pages={1695-7}
}
The present case report contributes new aspects to the etiology and the appearance of hypercalcemia at the onset of childhood acute lymphoblastic leukemia [ALL]. Malignancy associated hypercalcemia is often associated with an increase of Parathyroid hormone-related protein [PTHrP]. In our case PTHrP was normal but high levels of Parathormon [PTH] were measured. This increase of PTH was not due to hyperparathyroidism nor was it due to osteolytic lesions or metabolic disease interfering with bone… CONTINUE READING